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EMIS-2017: Planned national journal articles

To the end of 2019, we have provided EMIS-2017 national data to 39 partners, some of which have already published a national report (Canada, Estonia, Ireland, Switzerland). When these reports are published they will be available as PDFs here. National EMIS data for scientific articles can now be requested by members of the EMIS Network including merged 2010 and 2017 data for change analyses. Data request forms are available via e-mail. Please contact coordinator@emis-project.eu.

The following data access requests for national journal articles have been approved by the EMIS Editorial Board.

Lead author: Louis MacGregor
Dataset: EMIS-UK (2017)
Research question and objectives: To assess the association between substance use and chemsex (the use of substances including mephedrone, GHB and crystal meth around sexual intercourse) and diagnosis with (1) Gonorrhoea, syphilis, chlamydia and human papillomavirus and (2) hepatitis A, B and C within the men who have sex with men community in the UK.

Analytic plan: We will use logistic regression to build statistical models, inclusive of factors which are likely to be associated with the acquisition of included sexually transmitted infections (STIs). This work will split the STIs into two different groups consisting of (1) Gonorrhoea, syphilis, chlamydia and human papillomavirus and (2) hepatitis A, B and C. For each group we aim to publish a research article, with this data request therefore totalling data for two papers. In each paper, although we will be examining a list of multiple factors and their associations with STI acquisition, we will be paying special attention to chem-sex and substance use. Including use of individual substances and combinations of substances, plus route of ingestion. We will give demographics of our dataset population and use variables which are directly linked to sexual behaviours as our input variables for the models. We will both look at crude odd ratios and adjusted odds ratios.Within the paper on viral hepatitis, we also aim to comment on the prevalence of immunity and vaccination for hepatitis A and B, plus giving more detail on hepatitis C infections using variables listed in ‘Vaccinations and hepatitis’ in Q7.

Target journals: Lancet Infectious Diseases; International Journal of Epidemiology; Sexual Health

Date of approval: 29.11.2019

Lead author: Chris Noone
Dataset: EMIS-IE (2017)
Research question and objectives: The primary objective of this paper is to investigate the effects of minority stress on the health of gay, bisexual and other men who have sex with men in Ireland. This objective will be met by answering the following five research questions:

  1. What is the relationship between sexual identity and mental health outcomes?

  2. What is the relationship between experiencing distal minority stressors and mental health outcomes?

  3. What is the relationship between experiencing proximal minority stressors and mental health outcomes?

  4. What is the relationship between experiencing social support and mental health outcomes?

  5. To what extent does the intersection of marginalised identities affect mental health outcomes?

Analytic plan: The data will first be described using means, standard deviations and correlation coefficients, where appropriate. Each of the research questions will be answered using structural equation modelling. The analyses will be conducted in R Studio using the psych package to describe the data and the lavaan package for structural equation modelling. The analyses will be visualised using Ggplot2. The specific details regarding all analyses will be pre-registered on the Open Science Framework.

Target journals: Social Science and Medicine; Psychology of Sexual Orientation and Gender Diversity; LGBT Health
Date of approval: 29.11.2019

Lead author: Margot Annequin
Dataset: EMIS-FR (2017)
Research question and objectives: In France, PrEP was implemented in January 2016, has been fully reimbursed by the French national health insurance system since March 2017 and is recommended for men who have sex with men (MSM) with high risk of HIV infection. MSM represent 42% of new HIV diagnoses in France, thus it has been estimated that 50 000 MSM would be in PrEP need. However according to French social security data, 10 000 people have been reimbursed for PrEP as of the first semester of 2018. In order to increase PrEP coverage, we need to better characterise individuals who may benefit from PrEP but are not using it. Objectives of this study are to assess the percentage and describe MSM eligible to PrEP but non-users and to assess factors associated with being an eligible non PreP-user (ENPU).
Analytic plan: This analysis will be restricted to participants living in France, who declared being HIV-negative or never tested for HIV. Adapted to French guidelines, we will define PrEP eligibility as meeting at least one of three criteria: having condomless intercourse with ≥ 2 different partners in the last 12 months, having a history of post-exposure prophylaxis use or engaging in chemsex in the last 12 months We will assess the percentage of PrEP users and Eligible non PrEP-user (ENPU) amongst all French EMIS respondents, excluding those declaring HIV positive status. Socio-demographic characteristics, sexual behaviours and HIV knowledge will be compare between PrEP users and ENPU and factors associated with ENPU will assess using logistic regression models, comparing ENPU to PrEP users. This analysis will be restricted to participants living in France, who declared being HIV-negative or never tested for HIV. Adapted to French guidelines, we will define PrEP eligibility as meeting at least one of three criteria: having condomless intercourse with ≥ 2 different partners in the last 12 months, having a history of post-exposure prophylaxis use or engaging in chemsex in the last 12 months. We will assess the percentage of PrEP users and Eligible non PreP-user (ENPU) amongst all French EMIS respondents, excluding those declaring HIV positive status. Socio-demographic characteristics, sexual behaviours and HIV knowledge will be compare between PrEP users and ENPU and factors associated with ENPU will assess using logistic regression models, comparing ENPU to PrEP users. This analysis will be restricted to participants living in France, who declared being HIV-negative or never tested for HIV. Adapted to French guidelines, we will define PrEP eligibility as meeting at least one of three criteria: having condomless intercourse with ≥ 2 different partners in the last 12 months, having a history of post-exposure prophylaxis use or engaging in chemsex in the last 12 months. We will assess the percentage of PrEP users and Eligible non PreP-user (ENPU) amongst all French EMIS respondents, excluding those declaring HIV positive status. Socio-demographic characteristics, sexual behaviours and HIV knowledge will be compare between PrEP users and ENPU and factors associated with ENPU will assess using logistic regression models, comparing ENPU to PrEP users.
Target journal: AIDS

Date of approval: 29.03.2019